A77S (p.Ala77Ser) variant of DRD2 (D(2) dopamine receptor)
A77S (p.Ala77Ser) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
A77S (p.Ala77Ser) variant details
- p.Ala77Ser
- ExAC rs753530257
- TOPMed rs753530257
- gnomAD rs753530257
- Missense
- Variant Prioritization Score for Impact Estimate 0.55
- REVEL 0.43
- MetaLR 0.42
- MetaSVM 0.05
- CADD 25.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available