A29P (p.Ala29Pro) variant of DRD2 (D(2) dopamine receptor)
A29P (p.Ala29Pro) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
A29P (p.Ala29Pro) variant details
- p.Ala29Pro
- ExAC rs757338225
- TOPMed rs757338225
- gnomAD rs757338225
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.18
- MetaLR 0.04
- MetaSVM -1.00
- CADD 6.46
- PolyPhen-2 0.00
- SIFT 0.35
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available