A120G (p.Ala120Gly) variant of DRD2 (D(2) dopamine receptor)
A120G (p.Ala120Gly) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
A120G (p.Ala120Gly) variant details
- p.Ala120Gly
- TOPMed rs201724929
- gnomAD rs201724929
- Missense
- Variant Prioritization Score for Impact Estimate 0.809
- REVEL 0.81
- MetaLR 0.76
- MetaSVM 0.81
- CADD 29.60
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available