T93S (p.Thr93Ser) variant of DPYD (Q12882)
T93S (p.Thr93Ser) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
T93S (p.Thr93Ser) variant details
- p.Thr93Ser
- ExAC rs760553268
- gnomAD rs760553268
- Missense
- Variant Prioritization Score for Impact Estimate 0.734
- REVEL 0.72
- MetaLR 0.68
- MetaSVM 0.42
- CADD 25.80
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Ashkenazi Jewish population (allele frequency 7.7e-05)
- Structural context available