T31A (p.Thr31Ala) variant of DPYD (Q12882)
T31A (p.Thr31Ala) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
T31A (p.Thr31Ala) variant details
- p.Thr31Ala
- ExAC rs768501828
- TOPMed rs768501828
- gnomAD rs768501828
- Missense
- Variant Prioritization Score for Impact Estimate 0.525
- REVEL 0.49
- MetaLR 0.52
- MetaSVM 0.05
- CADD 23.70
- PolyPhen-2 0.38
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available