T27S (p.Thr27Ser) variant of DPYD (Q12882)
T27S (p.Thr27Ser) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
T27S (p.Thr27Ser) variant details
- p.Thr27Ser
- TOPMed rs770229152
- Missense
- Variant Prioritization Score for Impact Estimate 0.145
- REVEL 0.16
- MetaLR 0.08
- MetaSVM -0.98
- CADD 1.10
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
- Structural context available