T27I (p.Thr27Ile) variant of DPYD (Q12882)
T27I (p.Thr27Ile) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
T27I (p.Thr27Ile) variant details
- p.Thr27Ile
- Ensembl rs1672322439
- Missense
- Variant Prioritization Score for Impact Estimate 0.297
- REVEL 0.11
- MetaLR 0.21
- MetaSVM -0.84
- CADD 16.40
- PolyPhen-2 0.00
- SIFT 0.07
- Most common in the Ashkenazi Jewish population (allele frequency 5.1e-05)
- Structural context available