T132I (p.Thr132Ile) variant of DPYD (Q12882)
T132I (p.Thr132Ile) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
T132I (p.Thr132Ile) variant details
- p.Thr132Ile
- ExAC rs750224169
- gnomAD rs750224169
- Missense
- Variant Prioritization Score for Impact Estimate 0.686
- REVEL 0.70
- MetaLR 0.72
- MetaSVM 0.37
- CADD 24.70
- PolyPhen-2 0.95
- SIFT 0.01
- Most common in the South Asian population (allele frequency 0.00044)
- Structural context available