N108K (p.Asn108Lys) variant of DPYD (Q12882)
N108K (p.Asn108Lys) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
N108K (p.Asn108Lys) variant details
- p.Asn108Lys
- gnomAD rs762430779
- Missense
- Variant Prioritization Score for Impact Estimate 0.503
- REVEL 0.57
- MetaLR 0.55
- MetaSVM -0.01
- CADD 24.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.0011)
- Structural context available