N108D (p.Asn108Asp) variant of DPYD (Q12882)
N108D (p.Asn108Asp) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
N108D (p.Asn108Asp) variant details
- p.Asn108Asp
- gnomAD rs1485319921
- Missense
- Variant Prioritization Score for Impact Estimate 0.557
- REVEL 0.57
- MetaLR 0.57
- MetaSVM -0.01
- CADD 29.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Ashkenazi Jewish population (allele frequency 7.7e-05)
- Structural context available