N106K (p.Asn106Lys) variant of DPYD (Q12882)
N106K (p.Asn106Lys) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
N106K (p.Asn106Lys) variant details
- p.Asn106Lys
- TOPMed rs1264310175
- Missense
- Variant Prioritization Score for Impact Estimate 0.373
- REVEL 0.35
- MetaLR 0.26
- MetaSVM -0.69
- CADD 23.10
- PolyPhen-2 0.92
- SIFT 0.04
- Most common in the 1KG:GIH population (allele frequency 0.0053)
- Structural context available