M77V (p.Met77Val) variant of DPYD (Q12882)
M77V (p.Met77Val) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
M77V (p.Met77Val) variant details
- p.Met77Val
- 1000Genomes rs527580106
- ExAC rs527580106
- TOPMed rs527580106
- gnomAD rs527580106
- Missense
- Variant Prioritization Score for Impact Estimate 0.132
- REVEL 0.05
- MetaLR 0.09
- MetaSVM -1.10
- CADD 15.50
- PolyPhen-2 0.00
- SIFT 0.48
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available