M115V (p.Met115Val) variant of DPYD (Q12882)
M115V (p.Met115Val) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
M115V (p.Met115Val) variant details
- p.Met115Val
- ESP rs141462178
- ExAC rs141462178
- TOPMed rs141462178
- gnomAD rs141462178
- Missense
- Variant Prioritization Score for Impact Estimate 0.151
- REVEL 0.03
- MetaLR 0.03
- MetaSVM -1.00
- CADD 15.50
- PolyPhen-2 0.00
- SIFT 0.23
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available