L5F (p.Leu5Phe) variant of DPYD (Q12882)
L5F (p.Leu5Phe) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
L5F (p.Leu5Phe) variant details
- p.Leu5Phe
- gnomAD rs772097379
- Missense
- Variant Prioritization Score for Impact Estimate 0.563
- REVEL 0.42
- MetaLR 0.71
- MetaSVM 0.05
- CADD 27.90
- PolyPhen-2 0.82
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available