L16V (p.Leu16Val) variant of DPYD (Q12882)
L16V (p.Leu16Val) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
L16V (p.Leu16Val) variant details
- p.Leu16Val
- ESP rs150036960
- ExAC rs150036960
- gnomAD rs150036960
- Missense
- Variant Prioritization Score for Impact Estimate 0.506
- REVEL 0.43
- MetaLR 0.73
- MetaSVM 0.57
- CADD 25.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available