K89* (p.Lys89Ter) variant of DPYD (Q12882)
K89* (p.Lys89Ter) in DPYD (Q12882) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes structural context.
K89* (p.Lys89Ter) variant details
- p.Lys89Ter
- rs672601289
- ClinGen CA228177
- ClinVar RCV000086502
- TOPMed rs672601289
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.51
- AlphaMissense 0.65
- MetaLR 0.32
- MetaSVM -0.58
- PolyPhen-2 1.00
- SIFT 0.00
- EVE 0.80
- Structural context available