K42R (p.Lys42Arg) variant of DPYD (Q12882)
K42R (p.Lys42Arg) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
K42R (p.Lys42Arg) variant details
- p.Lys42Arg
- gnomAD rs1672319464
- Missense
- Variant Prioritization Score for Impact Estimate 0.584
- REVEL 0.52
- MetaLR 0.68
- MetaSVM 0.46
- CADD 26.40
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available