K38E (p.Lys38Glu) variant of DPYD (Q12882)
K38E (p.Lys38Glu) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
K38E (p.Lys38Glu) variant details
- p.Lys38Glu
- TOPMed rs1355470366
- Missense
- Variant Prioritization Score for Impact Estimate 0.644
- REVEL 0.72
- MetaLR 0.65
- MetaSVM 0.36
- CADD 26.70
- PolyPhen-2 0.81
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available