K34R (p.Lys34Arg) variant of DPYD (Q12882)
K34R (p.Lys34Arg) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
K34R (p.Lys34Arg) variant details
- p.Lys34Arg
- TOPMed rs1408654214
- gnomAD rs1408654214
- Missense
- Variant Prioritization Score for Impact Estimate 0.377
- REVEL 0.26
- MetaLR 0.24
- MetaSVM -0.67
- CADD 22.20
- PolyPhen-2 0.01
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.6e-05)
- Structural context available