I97V (p.Ile97Val) variant of DPYD (Q12882)
I97V (p.Ile97Val) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
I97V (p.Ile97Val) variant details
- p.Ile97Val
- TOPMed rs1664197872
- Missense
- Variant Prioritization Score for Impact Estimate 0.359
- REVEL 0.28
- MetaLR 0.25
- MetaSVM -0.60
- CADD 21.30
- PolyPhen-2 0.06
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available