I97T (p.Ile97Thr) variant of DPYD (Q12882)
I97T (p.Ile97Thr) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
I97T (p.Ile97Thr) variant details
- p.Ile97Thr
- ESP rs375990187
- TOPMed rs375990187
- Missense
- Variant Prioritization Score for Impact Estimate 0.81
- REVEL 0.93
- MetaLR 0.71
- MetaSVM 0.70
- CADD 26.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available