I116T (p.Ile116Thr) variant of DPYD (Q12882)
I116T (p.Ile116Thr) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
I116T (p.Ile116Thr) variant details
- p.Ile116Thr
- gnomAD rs1662930987
- Missense
- Variant Prioritization Score for Impact Estimate 0.744
- REVEL 0.90
- MetaLR 0.66
- MetaSVM 0.55
- CADD 26.60
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
- Structural context available