I101T (p.Ile101Thr) variant of DPYD (Q12882)
I101T (p.Ile101Thr) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
I101T (p.Ile101Thr) variant details
- p.Ile101Thr
- TOPMed rs1664196479
- Missense
- Variant Prioritization Score for Impact Estimate 0.809
- REVEL 0.92
- MetaLR 0.72
- MetaSVM 0.74
- CADD 28.00
- PolyPhen-2 1.00
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 3.4e-06)
- Structural context available