G68D (p.Gly68Asp) variant of DPYD (Q12882)
G68D (p.Gly68Asp) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
G68D (p.Gly68Asp) variant details
- p.Gly68Asp
- gnomAD rs1444666147
- Missense
- Variant Prioritization Score for Impact Estimate 0.482
- REVEL 0.34
- MetaLR 0.33
- MetaSVM -0.45
- CADD 23.40
- PolyPhen-2 0.30
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available