D84E (p.Asp84Glu) variant of DPYD (Q12882)
D84E (p.Asp84Glu) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
D84E (p.Asp84Glu) variant details
- p.Asp84Glu
- Ensembl rs1571280156
- Missense
- Variant Prioritization Score for Impact Estimate 0.588
- REVEL 0.59
- MetaLR 0.62
- MetaSVM 0.25
- CADD 23.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available