D61N (p.Asp61Asn) variant of DPYD (Q12882)
D61N (p.Asp61Asn) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
D61N (p.Asp61Asn) variant details
- p.Asp61Asn
- Ensembl rs1557992438
- Missense
- Variant Prioritization Score for Impact Estimate 0.651
- REVEL 0.55
- AlphaMissense 0.46
- MetaLR 0.61
- MetaSVM 0.39
- CADD 28.30
- PolyPhen-2 1.00
- Most common in the Non-Finnish European population (allele frequency 3.4e-06)
- Structural context available