D60N (p.Asp60Asn) variant of DPYD (Q12882)
D60N (p.Asp60Asn) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
D60N (p.Asp60Asn) variant details
- p.Asp60Asn
- gnomAD rs1160724559
- Missense
- Variant Prioritization Score for Impact Estimate 0.481
- REVEL 0.34
- MetaLR 0.34
- MetaSVM -0.57
- CADD 23.20
- PolyPhen-2 0.04
- SIFT 0.02
- Most common in the 1KG:IBS population (allele frequency 0.017)
- Structural context available