D37N (p.Asp37Asn) variant of DPYD (Q12882)
D37N (p.Asp37Asn) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
D37N (p.Asp37Asn) variant details
- p.Asp37Asn
- gnomAD rs984557299
- Missense
- Variant Prioritization Score for Impact Estimate 0.456
- REVEL 0.35
- MetaLR 0.12
- MetaSVM -0.86
- CADD 18.60
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available