D37H (p.Asp37His) variant of DPYD (Q12882)
D37H (p.Asp37His) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
D37H (p.Asp37His) variant details
- p.Asp37His
- gnomAD rs984557299
- Missense
- Variant Prioritization Score for Impact Estimate 0.446
- REVEL 0.30
- MetaLR 0.22
- MetaSVM -0.73
- CADD 21.80
- PolyPhen-2 0.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available