D37G (p.Asp37Gly) variant of DPYD (Q12882)
D37G (p.Asp37Gly) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
D37G (p.Asp37Gly) variant details
- p.Asp37Gly
- TOPMed rs1269099096
- gnomAD rs1269099096
- Missense
- Variant Prioritization Score for Impact Estimate 0.315
- REVEL 0.23
- MetaLR 0.22
- MetaSVM -0.75
- CADD 22.50
- PolyPhen-2 0.04
- SIFT 0.12
- Most common in the 1KG:GIH population (allele frequency 0.0053)
- Structural context available