D11N (p.Asp11Asn) variant of DPYD (Q12882)
D11N (p.Asp11Asn) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
D11N (p.Asp11Asn) variant details
- p.Asp11Asn
- cosmic curated COSV60081
- TOPMed rs1236287352
- gnomAD rs1236287352
- Missense
- Variant Prioritization Score for Impact Estimate 0.612
- REVEL 0.54
- MetaLR 0.56
- MetaSVM -0.24
- CADD 29.50
- PolyPhen-2 0.84
- SIFT 1.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
- Structural context available