A85S (p.Ala85Ser) variant of DPYD (Q12882)
A85S (p.Ala85Ser) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
A85S (p.Ala85Ser) variant details
- p.Ala85Ser
- ExAC rs757342874
- gnomAD rs757342874
- Missense
- Variant Prioritization Score for Impact Estimate 0.731
- REVEL 0.69
- MetaLR 0.73
- MetaSVM 0.51
- CADD 26.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the 1KG:GIH population (allele frequency 0.0053)
- Structural context available