A26T (p.Ala26Thr) variant of DPYD (Q12882)
A26T (p.Ala26Thr) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
A26T (p.Ala26Thr) variant details
- p.Ala26Thr
- ExAC rs766635900
- TOPMed rs766635900
- gnomAD rs766635900
- Missense
- Variant Prioritization Score for Impact Estimate 0.525
- REVEL 0.53
- MetaLR 0.48
- MetaSVM 0.05
- CADD 21.80
- PolyPhen-2 0.20
- SIFT 0.11
- Most common in the Ashkenazi Jewish population (allele frequency 7.7e-05)
- Structural context available