A10V (p.Ala10Val) variant of DPYD (Q12882)
A10V (p.Ala10Val) in DPYD (Q12882) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
A10V (p.Ala10Val) variant details
- p.Ala10Val
- gnomAD rs1347103587
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.15
- MetaLR 0.16
- MetaSVM -0.91
- CADD 22.70
- PolyPhen-2 0.00
- SIFT 0.36
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available