T3T (p.Thr3Thr) variant of DOCK8 (Q8NF50)
T3T (p.Thr3Thr) in DOCK8 (Q8NF50) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
T3T (p.Thr3Thr) variant details
- p.Thr3Thr
- gnomAD 9-214985-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.354
- MetaLR 0.02
- MetaSVM -1.04
- CADD 17.90
- PolyPhen-2 0.40
- MutPred 0.19
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available