S14G (p.Ser14Gly) variant of DNMT3A (Q9Y6K1)
S14G (p.Ser14Gly) in DNMT3A (Q9Y6K1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
S14G (p.Ser14Gly) variant details
- p.Ser14Gly
- gnomAD rs1373614770
- Missense
- Variant Prioritization Score for Impact Estimate 0.27
- REVEL 0.16
- MetaLR 0.54
- MetaSVM -0.48
- CADD 20.40
- PolyPhen-2 0.00
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available