P41S (p.Pro41Ser) variant of DNMT3A (Q9Y6K1)
P41S (p.Pro41Ser) in DNMT3A (Q9Y6K1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
P41S (p.Pro41Ser) variant details
- p.Pro41Ser
- gnomAD rs1391800442
- Missense
- Variant Prioritization Score for Impact Estimate 0.273
- REVEL 0.14
- MetaLR 0.53
- MetaSVM -0.26
- CADD 15.00
- PolyPhen-2 0.00
- SIFT 0.11
- Population evidence available
- Structural context available