M4L (p.Met4Leu) variant of DNMT3A (Q9Y6K1)
M4L (p.Met4Leu) in DNMT3A (Q9Y6K1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
M4L (p.Met4Leu) variant details
- p.Met4Leu
- Ensembl rs2149429139
- Missense
- Variant Prioritization Score for Impact Estimate 0.578
- REVEL 0.55
- MetaLR 0.67
- MetaSVM 0.52
- CADD 21.60
- PolyPhen-2 0.01
- SIFT 0.07
- Population evidence available
- Structural context available