G8V (p.Gly8Val) variant of DNMT3A (Q9Y6K1)
G8V (p.Gly8Val) in DNMT3A (Q9Y6K1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
G8V (p.Gly8Val) variant details
- p.Gly8Val
- cosmic curated COSV10878
- Missense
- Variant Prioritization Score for Impact Estimate 0.683
- REVEL 0.57
- MetaLR 0.80
- MetaSVM 0.80
- CADD 24.70
- PolyPhen-2 0.95
- SIFT 0.05
- Population evidence available
- Structural context available