G8D (p.Gly8Asp) variant of DNMT3A (Q9Y6K1)
G8D (p.Gly8Asp) in DNMT3A (Q9Y6K1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
G8D (p.Gly8Asp) variant details
- p.Gly8Asp
- Ensembl rs2149429095
- Missense
- Variant Prioritization Score for Impact Estimate 0.677
- REVEL 0.56
- MetaLR 0.80
- MetaSVM 0.81
- CADD 24.80
- PolyPhen-2 0.93
- SIFT 0.00
- Population evidence available
- Structural context available