G83V (p.Gly83Val) variant of DNMT3A (Q9Y6K1)
G83V (p.Gly83Val) in DNMT3A (Q9Y6K1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
G83V (p.Gly83Val) variant details
- p.Gly83Val
- cosmic curated COSV10439
- Missense
- Variant Prioritization Score for Impact Estimate 0.418
- REVEL 0.26
- MetaLR 0.59
- MetaSVM 0.06
- CADD 20.70
- PolyPhen-2 0.00
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available