E21K (p.Glu21Lys) variant of DNMT3A (Q9Y6K1)
E21K (p.Glu21Lys) in DNMT3A (Q9Y6K1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
E21K (p.Glu21Lys) variant details
- p.Glu21Lys
- cosmic curated COSV53077
- Missense
- Variant Prioritization Score for Impact Estimate 0.197
- CADD 16.40
- SIFT 0.60
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available