D25V (p.Asp25Val) variant of DNMT3A (Q9Y6K1)
D25V (p.Asp25Val) in DNMT3A (Q9Y6K1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
D25V (p.Asp25Val) variant details
- p.Asp25Val
- gnomAD rs1477239833
- Missense
- Variant Prioritization Score for Impact Estimate 0.423
- REVEL 0.34
- MetaLR 0.58
- MetaSVM 0.05
- CADD 23.50
- PolyPhen-2 0.04
- SIFT 0.36
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.2e-05)
- Structural context available