D11E (p.Asp11Glu) variant of DNMT3A (Q9Y6K1)
D11E (p.Asp11Glu) in DNMT3A (Q9Y6K1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
D11E (p.Asp11Glu) variant details
- p.Asp11Glu
- cosmic curated COSV53069
- Missense
- Variant Prioritization Score for Impact Estimate 0.467
- REVEL 0.37
- MetaLR 0.77
- MetaSVM 0.31
- CADD 23.00
- PolyPhen-2 0.42
- SIFT 0.08
- Population evidence available
- Structural context available