A84V (p.Ala84Val) variant of DNMT3A (Q9Y6K1)
A84V (p.Ala84Val) in DNMT3A (Q9Y6K1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
A84V (p.Ala84Val) variant details
- p.Ala84Val
- ExAC rs763793247
- gnomAD rs763793247
- Missense
- Variant Prioritization Score for Impact Estimate 0.402
- REVEL 0.28
- MetaLR 0.52
- MetaSVM -0.49
- CADD 22.10
- PolyPhen-2 0.00
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available