A3D (p.Ala3Asp) variant of DNMT3A (Q9Y6K1)
A3D (p.Ala3Asp) in DNMT3A (Q9Y6K1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
A3D (p.Ala3Asp) variant details
- p.Ala3Asp
- Ensembl rs2034259976
- Missense
- Variant Prioritization Score for Impact Estimate 0.452
- REVEL 0.45
- MetaLR 0.65
- MetaSVM -0.06
- CADD 21.10
- PolyPhen-2 0.00
- SIFT 0.09
- Population evidence available
- Structural context available