Y11H (p.Tyr11His) variant of DMD (Dystrophin)

Name: DMD Y11H (p.Tyr11His) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-09
License: https://catvariant.com/terms-of-use

Y11H (p.Tyr11His) in DMD (Dystrophin) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.

Y11H (p.Tyr11His) variant details

p.Tyr11His
NCI-TCGA Cosmic COSV5586
cosmic curated COSV55863
Variant assessed as somatic; moderate impact.
Missense
Variant Prioritization Score for Impact Estimate 0.515
CADD 18.40
SIFT 1.00
UniProt: Variant assessed as somatic; moderate impact.
Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
Structural context available