R150C (p.Arg150Cys) variant of DLG4 (Disks large homolog 4)
R150C (p.Arg150Cys) in DLG4 (Disks large homolog 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
R150C (p.Arg150Cys) variant details
- p.Arg150Cys
- cosmic curated COSV57238
- Missense
- Variant Prioritization Score for Impact Estimate 0.607
- REVEL 0.46
- CADD 29.20
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available