P92S (p.Pro92Ser) variant of DLG4 (Disks large homolog 4)
P92S (p.Pro92Ser) in DLG4 (Disks large homolog 4) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
P92S (p.Pro92Ser) variant details
- p.Pro92Ser
- NCI-TCGA Cosmic COSV5723
- cosmic curated COSV57236
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.43
- REVEL 0.20
- CADD 23.80
- PolyPhen-2 0.44
- SIFT 0.16
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available