P21T (p.Pro21Thr) variant of DLG4 (Disks large homolog 4)
P21T (p.Pro21Thr) in DLG4 (Disks large homolog 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, experimental measurements, and structural context.
P21T (p.Pro21Thr) variant details
- p.Pro21Thr
- cosmic curated COSV10513
- Missense
- Variant Prioritization Score for Impact Estimate 0.47
- REVEL 0.29
- CADD 23.50
- PolyPhen-2 0.07
- SIFT 0.02
- Population evidence available
- Structural context available
- DLG4 PDZ domain domainome 1.0: score -0.71